Resistance to the macrolide antibiotic tylosin is conferred by single methylations at 23S rRNA nucleotides G748 and A2058 acting in synergy
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference51 articles.
1. HOW ANTIBIOTIC-PRODUCING ORGANISMS AVOID SUICIDE
2. Genetics of Streptomyces Fradiae and Tylosin Biosynthesis
3. Multiple regulatory genes in the tylosin biosynthetic cluster of Streptomyces fradiae
4. Cloning of tlrD, a fourth resistance gene, from the tyiosin producer, Streptomyces fradiae
5. Methylation of 23S rRNA caused by tlrA (ermSF), a tylosin resistance determinant from Streptomyces fradiae
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