Catecholamine-induced lipolysis causes mTOR complex dissociation and inhibits glucose uptake in adipocytes

Author:

Mullins Garrett R.,Wang Lifu,Raje Vidisha,Sherwood Samantha G.,Grande Rebecca C.,Boroda Salome,Eaton James M.,Blancquaert Sara,Roger Pierre P.,Leitinger Norbert,Harris Thurl E.

Funder

American Diabetes Association (ADA)

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

American Heart Association (AHA)

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference44 articles.

1. Epinephrine-induced Insulin Resistance in Man

2. Catecholamines inhibit insulin-stimulated glucose transport in adipocytes, in the presence of adenosine deaminase

3. Counter-regulation of insulin-stimulated glucose transport by catecholamines in the isolated rat adipose cell;Smith;J Biol Chem,1984

4. Regulation of insulin-stimulated glucose transport in the isolated rat adipocyte. cAMP-independent effects of lipolytic and antilipolytic agents;Kuroda;J Biol Chem,1987

5. Activation of adenylate cyclase and inhibition of glucose transport in rat adipocytes by forskolin analogues: Structural determinants for distinct sites of action;Joost;Mol Pharmacol,1988

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