Genetics, leadership position, and well-being: An investigation with a large-scale GWAS-Reference-Cited by-同舟云学术

Genetics, leadership position, and well-being: An investigation with a large-scale GWAS

Published:2022-03-14 Issue:12 Volume:119 Page:
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proc. Natl. Acad. Sci. U.S.A.

Author:

Song Zhaoli¹^ORCID,Li Wen-Dong²,Jin Xuye³,Ying Junbiao³,Zhang Xin²,Song Ying³,Li Hengtong³^ORCID,Fan Qiao⁴

Affiliation:

1. Department of Management and Organization, National University of Singapore, 119245, Singapore

2. Department of Management, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China

3. Department of Statistics and Data Science, National University of Singapore, 117546, Singapore

4. Centre for Quantitative Medicine, Duke-NUS Medical School, 169857, Singapore

Abstract

Significance Our study presents the largest whole-genome investigation of leadership phenotypes to date. We identified genome-wide significant loci for leadership phenotypes, which are overlapped with top hits for bipolar disorder, schizophrenia, and intelligence. Our study demonstrated the polygenetic nature of leadership, the positive genetic correlations between leadership traits and a broad range of well-being indicators, and the unique association of leadership with well-being after accounting for genetic influences related to other socioeconomic status measures. Our findings offer insights into the biological underpinnings of leadership.

Funder

Ministry of Education - Singapore

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Link

https://pnas.org/doi/pdf/10.1073/pnas.2114271119

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