Author:
Hu Yibo,Wu Qi,Ma Shuai,Ma Tianxiao,Shan Lei,Wang Xiao,Nie Yonggang,Ning Zemin,Yan Li,Xiu Yunfang,Wei Fuwen
Abstract
Phenotypic convergence between distantly related taxa often mirrors adaptation to similar selective pressures and may be driven by genetic convergence. The giant panda (Ailuropoda melanoleuca) and red panda (Ailurus fulgens) belong to different families in the order Carnivora, but both have evolved a specialized bamboo diet and adaptive pseudothumb, representing a classic model of convergent evolution. However, the genetic bases of these morphological and physiological convergences remain unknown. Through de novo sequencing the red panda genome and improving the giant panda genome assembly with added data, we identified genomic signatures of convergent evolution. Limb development genesDYNC2H1andPCNThave undergone adaptive convergence and may be important candidate genes for pseudothumb development. As evolutionary responses to a bamboo diet, adaptive convergence has occurred in genes involved in the digestion and utilization of bamboo nutrients such as essential amino acids, fatty acids, and vitamins. Similarly, the umami taste receptor geneTAS1R1has been pseudogenized in both pandas. These findings offer insights into genetic convergence mechanisms underlying phenotypic convergence and adaptation to a specialized bamboo diet.
Funder
National Natural Science Foundation of China
Chinese Ministry of Science and Technology | Department of S and T for Social Development
Chinese Academy of Sciences
Publisher
Proceedings of the National Academy of Sciences
Cited by
187 articles.
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