Conversion of mammalian 3alpha -hydroxysteroid dehydrogenase to 20alpha -hydroxysteroid dehydrogenase using loop chimeras: Changing specificity from androgens to progestins-Reference-Cited by-同舟云学术

Conversion of mammalian 3alpha -hydroxysteroid dehydrogenase to 20alpha -hydroxysteroid dehydrogenase using loop chimeras: Changing specificity from androgens to progestins

Published:1999-09-28 Issue:20 Volume:96 Page:11161-11166
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proceedings of the National Academy of Sciences

Author:

Ma H.,Penning T. M.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference31 articles.

1. Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3α-hydroxysteroid/dihydrodiol dehydrogenase

2. The structure of a complex of human 17β-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors

3. Atomic structure of progesterone complexed with its receptor

4. Molecular basis of agonism and antagonism in the oestrogen receptor

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