Molecular basis of agonism and antagonism in the oestrogen receptor

Author:

Brzozowski Andrzej M.,Pike Ashley C. W.,Dauter Zbigniew,Hubbard Roderick E.,Bonn Tomas,Engström Owe,Öhman Lars,Greene Geoffrey L.,Gustafsson Jan-Åke,Carlquist Mats

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference29 articles.

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2. Tsai, M.-J. & O'Malley, B. W. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu. Rev. Biochem. 63, 451–486 (1994).

3. Katzenellenbogen, J. A., O'Malley, B. W. & Katzenellenbogen, B. S. Tripartite steroid hormone receptor pharmacology: Interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones. Mol. Endocrinol. 10, 119–131 (1996).

4. Beato, M. & Sánchez-Pacheco, A. Interaction of steroid hormone receptors with the transcription initiation complex. Endocr. Rev. 17, 587–609 (1996).

5. Grese, T. A. et al. Structure-activity relationships of selective estrogen receptor modulators: Modifications to the 2-arylbenzothiophene core of raloxifene. J. Med. Chem. 40, 146–167 (1997).

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