In silico selection of therapeutic antibodies for development: Viscosity, clearance, and chemical stability-Reference-Cited by-同舟云学术

In silico selection of therapeutic antibodies for development: Viscosity, clearance, and chemical stability

Published:2014-12-15 Issue:52 Volume:111 Page:18601-18606
ISSN:0027-8424
Container-title:Proceedings of the National Academy of Sciences
language:en
Short-container-title:Proc Natl Acad Sci USA

Author:

Sharma Vikas K.,Patapoff Thomas W.,Kabakoff Bruce,Pai Satyan,Hilario Eric,Zhang Boyan,Li Charlene,Borisov Oleg,Kelley Robert F.,Chorny Ilya,Zhou Joe Z.,Dill Ken A.,Swartz Trevor E.

Publisher

Proceedings of the National Academy of Sciences

Subject

Multidisciplinary

Reference31 articles.

1. Something new under the skin

2. Challenges in the development of high protein concentration formulations

3. Monoclonal Antibody Pharmacokinetics and Pharmacodynamics

4. Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration

5. Computational methods to predict therapeutic protein aggregation;Buck;Therapeutic Proteins: Methods and Protocols,2012

Cited by 209 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A framework for the biophysical screening of antibody mutations targeting solvent-accessible hydrophobic and electrostatic patches for enhanced viscosity profiles;Computational and Structural Biotechnology Journal;2024-12

2. AI-accelerated therapeutic antibody development: practical insights;Frontiers in Drug Discovery;2024-09-03

3. Leveraging Multi-Modal Feature Learning for Predictions of Antibody Viscosity;2024-09-01

4. Cellular Neonatal Fc Receptor Recycling Efficiencies can Differentiate Target-Independent Clearance Mechanisms of Monoclonal Antibodies;Journal of Pharmaceutical Sciences;2024-09

5. Developability considerations for bispecific and multispecific antibodies;mAbs;2024-08-27