Developability considerations for bispecific and multispecific antibodies
Author:
Affiliation:
1. AbCellera Biologics Inc, Vancouver, BC, Canada
Publisher
Informa UK Limited
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2024.2394229
Reference261 articles.
1. Design and Efficacy of a Monovalent Bispecific PD-1/CTLA4 Antibody That Enhances CTLA4 Blockade on PD-1+ Activated T Cells
2. Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET
3. Emicizumab Prophylaxis in Hemophilia A with Inhibitors
4. A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells
5. CLN-978, a novel half-life extended CD19/CD3/HSA-specific T cell-engaging antibody construct with potent activity against B-cell malignancies with low CD19 expression
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