Juxtamembranous aspartic acid in Insig-1 and Insig-2 is required for cholesterol homeostasis
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference27 articles.
1. Protein Sensors for Membrane Sterols
2. Regulation of the mevalonate pathway
3. Gp78, a Membrane-Anchored Ubiquitin Ligase, Associates with Insig-1 and Couples Sterol-Regulated Ubiquitination to Degradation of HMG CoA Reductase
4. The Ubiquitin-Proteasome Pathway Mediates the Regulated Degradation of Mammalian 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase
5. Accelerated Degradation of HMG CoA Reductase Mediated by Binding of Insig-1 to Its Sterol-Sensing Domain
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