Multiple activation pathways of benzene leading to products with varying genotoxic characteristics.

Author:

Glatt H1,Padykula R1,Berchtold G A1,Ludewig G1,Platt K L1,Klein J1,Oesch F1

Affiliation:

1. Department of Toxicology, University of Mainz, Federal Republic of Germany.

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference33 articles.

1. Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons;Conney A. H;Cancer Res.,1982

2. Structural and metabolic parameters governing the mutagenicity of polycyclic aromatic hydrocarbons. In: Chemical Mutagens: Principles and Methods for Their Detection, Vol. 10 (F. J. de Serres, Ed.), Plenum;Glatt H. R.;New York,1986

3. Cell transformation by chemical agents — A review and analysis of the literature

4. Mutagenic and cell-transforming activities of triol-epoxides as compared to other chrysene metabolites;Glatt H. R.;Cancer Res.,1986

5. Activation of c-Ha-ras-1 proto-oncogene by in vitro modification with a chemical carcinogen, benzo(a)pyrene diol-epoxide

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