Beyond the RfD: Broad Application of a Probabilistic Approach to Improve Chemical Dose–Response Assessments for Noncancer Effects-Reference-Cited by-同舟云学术

Beyond the RfD: Broad Application of a Probabilistic Approach to Improve Chemical Dose–Response Assessments for Noncancer Effects

Published:2018-06-15 Issue:6 Volume:126 Page:067009
ISSN:0091-6765
Container-title:Environmental Health Perspectives
language:en
Short-container-title:Environ Health Perspect

Author:

Chiu Weihsueh A.¹,Axelrad Daniel A.²,Dalaijamts Chimeddulam¹,Dockins Chris²,Shao Kan³,Shapiro Andrew J.⁴,Paoli Greg⁵

Affiliation:

1. Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA

2. Office of Policy (1809T), U.S. Environmental Protection Agency, Washington, District of Columbia, USA

3. Department of Environmental and Occupational Health, Indiana University School of Public-Bloomington, Bloomington, Indiana, USA

4. National Toxicology Program, National Institute for Environmental Health Sciences, Research Triangle Park, North Carolina, USA

5. Risk Sciences International, Ottawa, Ontario, Canada

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference46 articles.

1. Population-Based in Vitro Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study

2. Noncancer Risk Assessment: A Probabilistic Alternative to Current Practice

3. Assessment of potential risk levels associated with U.S. Environmental Protection Agency reference values.

4. Chiu W. 2018a. APROBAweb: an interactive web application for probabilistic hazard characterization/dose-response assessment. https://wchiu.shinyapps.io/APROBAweb/ [accessed 16 April 2018].

5. Chiu W. 2018b. Data and code for probabilistic RfD calculations. https://github.com/wachiuphd/Probabilistic-RfD [accessed 16 April 2018].

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