Computational Model of Steroidogenesis in Human H295R Cells toPredict Biochemical Response to Endocrine-Active Chemicals: Model Developmentfor Metyrapone-Reference-Cited by-同舟云学术

Computational Model of Steroidogenesis in Human H295R Cells toPredict Biochemical Response to Endocrine-Active Chemicals: Model Developmentfor Metyrapone

Published:2010-02 Issue:2 Volume:118 Page:265-272
ISSN:0091-6765
Container-title:Environmental Health Perspectives
language:en
Short-container-title:Environmental Health Perspectives

Author:

Breen Michael S.¹,Breen Miyuki²³,Terasaki Natsuko⁴,Yamazaki Makoto⁴,Conolly Rory B.²

Affiliation:

1. National Exposure Research Laboratory

2. National Center for Computational Toxicology, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA

3. Biomathematics Program, Department of Statistics, North Carolina State University, Raleigh, North Carolina, USA

4. Safety Research Laboratory, Mitsubishi Tanabe Pharma Corporation, Kisarazu, Chiba, Japan

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference41 articles.

1. Minireview: Cellular Redox State Regulates Hydroxysteroid Dehydrogenase Activity and Intracellular Hormone Potency

2. Mathematical model of steroidogenesis in rat and rabbit testes.;Becker S;Am J Physiol,1980

3. Mechanistic Computational Model of Ovarian Steroidogenesis to Predict Biochemical Responses to Endocrine Active Compounds

4. A Receptor-Mediated Pathway for Cholesterol Homeostasis

5. Cholesterol Sensing, Trafficking, and Esterification

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