Age- and Concentration-Dependent Elimination Half-Life of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Seveso Children

Author:

Kerger Brent D.1,Leung Hon-Wing2,Scott Paul3,Paustenbach Dennis J.3,Needham Larry L.4,Patterson Donald G.4,Gerthoux Pier M.5,Mocarelli Paolo5

Affiliation:

1. Health Science Resource Integration, Tallahassee, Florida, USA

2. Private Consultant, Danbury, Connecticut, USA

3. ChemRisk, San Francisco, California, USA

4. Centers for Disease Control and Prevention, Atlanta, Georgia, USA

5. Department of Laboratory Medicine, University Milano-Bicocca, Hospital of Desio, Desio–Milano, Italy

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference32 articles.

1. Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: Insights into the measurement of hepatic cytochrome P450 1A2 induction*

2. Agency for Toxic Substances and Disease Registry 1998. Toxicological Profile for Chlorinated Dibenzo- p -Dioxins. Atlanta GA:Agency for Toxic Substances and Disease Registry.

3. Concentration-dependent TCDD elimination kinetics in humans: toxicokinetic modeling for moderately to highly exposed adults from Seveso, Italy and Vienna, Austria, and impact on dose estimates for the NIOSH cohort;Aylward LL;J Exposure Anal Environ Epidemiol,2005

4. Modeling of the Toxicokinetics of Polychlorinated Dibenzo-p-dioxins and Dibenzofurans in Mammalians, Including Humans

5. Modeling of the Toxicokinetics of Polychlorinated Dibenzo-p-dioxins and Dibenzofurans in Mammalians, Including Humans

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