B-lymphocyte stimulator (BLyS) -specific inhibitor (Belimumab)
Author:
Affiliation:
1. KKR Sapporo Medical Center, Department of Pediatrics
Publisher
Japanese Society of Pediatric Allergy and Clinical Immunology
Link
https://www.jstage.jst.go.jp/article/jspaci/38/3/38_301/_pdf
Reference17 articles.
1. 1) Brunner HI, et al. Safety and efficacy of intravenous belimumab in children with systemic lupus erythematosus: results from a randomised, placebo-controlled trial. Ann Rheum Dis 2020;79:1340-1348.
2. 2) Mackay F, et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 1999;190:1697-1710.
3. 3) Navarra SV, et al. Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial. Lancet 2011;377:721-731.
4. 4) Furie R, et al. A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus. Arthritis Rheum 2011;63:3918-3930.
5. 5) Zhang F, et al. A pivotal phase III, randomised, placebo-controlled study of belimumab in patients with systemic lupus erythematosus located in China, Japan and South Korea. Ann Rheum Dis 2018;77:355-363.
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