Abstract
ABSTRACTExperiments were conducted to assess the effect of sublethal concentrations of niclosamide on the infectivity ofSchistosoma mansonicercariae. Exposure of cercariae to 0.02 mg/1 and 0.05 mg/1 of niclosamide, respectively, for only two hours increased their mortality during penetration of mammalian host skin. The observed increase in mortality in the skin resulted in a consequent reduction of adult worm recovery from the liver and mesenteric veins of animals infected with the treated cercariae.
Publisher
Cambridge University Press (CUP)
Subject
Animal Science and Zoology,General Medicine,Parasitology
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