Author:
Grufferty Roger C.,Condon Seamus
Abstract
SUMMARYHydrogen peroxide accumulated in aerated cultures ofStreptococcus lactisC10, the amount depending on the sugar being utilized. When the energy source was galactose or (to a lesser extent) lactose or maltose, H2O2reached autoinhibitory levels. With glucose, H2O2reached levels which did not cause obvious inhibition, and then declined. Washed cell suspensions utilized several media ingredients including glucose, galactose and yeast extract as substrates for O2uptake, but cell-free extracts utilized none of these. The only substrate which supported O2uptake by cell-free extracts was NADH. The activity of NADH oxidase was not affected by several intermediates of carbohydrate metabolism. Evidence was obtained to show that its synthesis was regulated via induction by O2with an overriding catabolite repression type control, when cells were grown at the expense of glucose.
Publisher
Cambridge University Press (CUP)
Subject
Animal Science and Zoology,General Medicine,Food Science
Cited by
32 articles.
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