Variation in virulence of bovine rotaviruses

Author:

Bridger J. C.,Pocock D. H.

Abstract

SUMMARYForty-six gnotobiotic calves aged less than 16 days or 42–116 days were infected with three strains of bovine rotavirus designated C3–160, CP-1 and PP-1. Each virus was passaged and cloned in cell culture (cloned viruses) but CP-1 and PP-1 Were also used before culture (faecal viruses).Infection of calves aged less than 16 days with faecal or cloned CP-1 caused disease whereas cloned C3–160 and faecal or cloned PP-1 caused subclinical infections. The clinical signs of disease were change in faecal colour to pale yellow or cream, increase of 2- to 7-fold in the volume of faecal output and, usually, anorexia. With the virulent CP-1 virus and the avirulent C3–160, similar amounts of virus were excreted in the faeces for 4–6 days.Infection of calves aged 56–116days with faecal CP-1 produced disease of similar severity to that seen in calves aged 7–10 days infected with the same virus. No differences in clinical signs, virus excretion or levels of convalescent antibody were seen between the two groups. With cloned CP-1, 5 of 8 older calves developed disease but 3 showed only mild signs of infection.It was concluded that two strains of rotavirus caused sub-clinical infections in young calves while a third was virulent in calves up to at least 116 days of age.

Publisher

Cambridge University Press (CUP)

Subject

Public Health, Environmental and Occupational Health,Immunology

Reference26 articles.

1. Rotavirusinfektionen in einem grüsseren Rhinderbestand;Sibalin;Weiner Tierärztliche Monatatsschrift,1980

2. Development of immunity to porcine rotavirus in piglets protected from disease by bovine colostrum;Bridger;Infection and Immunity,1981

3. The experimental production of diarrhoea in colostrum deprived axenic and gnotoxenic calves with enteropathogenic E. coli, rotavirus, coronavirus and in combined infection of rotavirus and E. coli;Gouet;Annales de Recherche Veterinaire,1978

4. Van Opdenbosch E. & Wellemans G. (1982). Perspectives in the prevention of viral neonatal calf diarrhoea. Proceedings of the XIIth World Congress on Diseases of Cattle, p. 374.

Cited by 41 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3