Author:
TROTT D. J.,COMBS B. G.,MIKOSZA A. S. J.,OXBERRY S. L.,ROBERTSON I. D.,PASSEY M.,TAIME J.,SEHUKO R.,ALPERS M. P.,HAMPSON D. J.
Abstract
In a survey of five villages in the Eastern Highlands of Papua
New Guinea, Serpulina pilosicoli
was isolated from rectal swabs from 113 of 496 individuals (22·8%).
Colonization rates ranged
from 22·6–30·1% in four of the villages but was only
8·6% in the other village. In comparison
colonization was demonstrated in only 5 of 54 indigenous people
(9·3%) and none of 76 non-indigenous people living in an urban environment
in the same region. Colonization did not
relate to reported occurrence of diarrhoea, age, sex, or length of time
resident in a village. A
second set of 94 faecal specimens was collected from 1 village 6 weeks
after
the first set. S.
pilosicoli was isolated from 27 of 29 individuals (93·1%) who
were positive on the first
sampling and from 7 of 65 individuals (10·8%) who previously were
negative. In this case,
isolates were significantly more common in watery stools than in normal
stools. The annual
incidence of infection in the village was calculated as 93·6%, with
an average duration of
infection of 117 days. S. pilosicoli could not be isolated
from any village pig (n=126) despite
its confirmed presence in 17 of 50 commercial pigs (34·0%) sampled
at a
local piggery. Four of
76 village dogs (5·3%) and 1 of 2 village ducks were colonized with
S. pilosicoli, suggesting the
possibility of cross transmission between humans and animals.
Publisher
Cambridge University Press (CUP)
Subject
Infectious Diseases,Epidemiology
Cited by
72 articles.
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