Feasibility study of laser-driven neutron sources for pharmaceutical applications
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Published:2023
Issue:
Volume:11
Page:
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ISSN:2095-4719
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Container-title:High Power Laser Science and Engineering
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language:en
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Short-container-title:High Pow Laser Sci Eng
Author:
Mori TakatoORCID,
Yogo AkifumiORCID,
Arikawa Yasunobu,
Hayakawa Takehito,
Mirfayzi Seyed R.ORCID,
Lan Zechen,
Wei TianyunORCID,
Abe Yuki,
Nakai Mitsuo,
Mima Kunioki,
Nishimura Hiroaki,
Fujioka Shinsuke,
Kodama Ryosuke
Abstract
Abstract
We predict the production yield of a medical radioisotope
${}^{67}$
Cu using
${}^{67}$
Zn(n, p)
${}^{67}$
Cu and
${}^{68}$
Zn(n, pn)
${}^{67}$
Cu reactions with fast neutrons provided from laser-driven neutron sources. The neutrons were generated by the p+
${}^9\mathrm{Be}$
and d+
${}^9$
Be reactions with high-energy ions accelerated by laser–plasma interaction. We evaluated the yield to be (3.3
$\pm$
0.5)
$\times$
10
${}^5$
atoms for
${}^{67}$
Cu, corresponding to a radioactivity of 1.0
$\pm$
0.2 Bq, for a Zn foil sample with a single laser shot. Using a simulation with this result, we estimated
${}^{67}$
Cu production with a high-frequency laser. The result suggests that it is possible to generate
${}^{67}$
Cu with a radioactivity of 270 MBq using a future laser system with a frequency of 10 Hz and 10,000-s radiation in a hospital.
Funder
Ministry of Education, Culture, Sports, Science and Technology
Japan Society for the Promotion of Science
Publisher
Cambridge University Press (CUP)
Subject
Nuclear Energy and Engineering,Nuclear and High Energy Physics,Atomic and Molecular Physics, and Optics,Electronic, Optical and Magnetic Materials