Glycine and formic hydrogenlyase

Abstract

1. A strain ofBoot, coliadapted to growth in high glycine concentrations, which had lost the power of producing ‘gas’ from sugars, was shown to be devoid of formic hydrogenlyase.2. Formic acid was prominent among the products of fermentation of sugars by this strain.3. The appearance of formic hydrogenlyasein vitro, in bacteria grown in such a way as not to contain the enzyme, was inhibited by glycine at high concentrations.One of us (J. G.) is indebted to the Medical Research Council for a grant-in-aid for expenses.