機能性腸内代謝物素材ウロリチンAの開発
Author:
Affiliation:
1. Healthcare SBU, DAICEL CORPORATION
2. Production Division, DAICEL CORPORATION
3. Innovation and Business Development Headquarters, DAICEL CORPORATION
Publisher
Japanese Society of Nutrition and Food Science
Subject
General Materials Science
Link
https://www.jstage.jst.go.jp/article/jsnfs/76/6/76_383/_pdf
Reference17 articles.
1. 1) Ryu D, Mouchiroud L, Andreux PA, Katsyuba E, Moullan N, Nicolet-Dit-Félix AA, Williams EG, Jha P, Sasso GL, Huzard D, Aebischer P, Sandi C, Rinsch C, Auwerx J (2016) Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents. Nat Med 22: 879-88.
2. 2) Ishimoto H, Tai A, Yoshimura M, Amakura Y, Yoshida T, Hatano T, Ito H (2012) Antioxidative properties of functional polyphenols and their metabolites assessed by an ORAC assay. Biosci Biotechnol Biochem 76: 395-9.
3. 3) Ito H, Li P, Koreishi M, Nagatomo A, Nishida N, Yoshida T (2014) Ellagitannin oligomers and a neolignan from pomegranate arils and their inhibitory effects on the formation of advanced glycation end products. Food Chem 152: 323-30.
4. 4) Ishimoto H, Shibata M, Myojin Y, Ito H, Sugimoto Y, Tai A, Hatano T (2011) In vivo anti-inflammatory and antioxidant properties of ellagitannin metabolite urolithin A. Bioorg Med Chem Lett 21: 5901-4.
5. 5) Singh R, Chandrashekharappa S, Bodduluri SR, Baby BV, Hegde B, Kotla NG, Hiwale AA, Saiyed T, Patel P, Vijay-Kumar M, Langille MGI Douglas GM, Cheng X, Rouchka EC, Waigel SJ, Dryden GW, Alatassi H, Zhang HG, Haribabu B, Vemula PK, Jala VR (2019) Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway. Nat Commun 10: 89.
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