Factors affecting the electrocardiographic QT interval in malaria: A systematic review and meta-analysis of individual patient data

Author:

Chan Xin Hui S.ORCID,Win Yan NaungORCID,Haeusler Ilsa L.ORCID,Tan Jireh Y.,Loganathan Shanghavie,Saralamba Sompob,Chan Shu Kiat S.,Ashley Elizabeth A.ORCID,Barnes Karen I.ORCID,Baiden Rita,Bassi Peter U.,Djimde AbdoulayeORCID,Dorsey GrantORCID,Duparc StephanORCID,Hanboonkunupakarn BorimasORCID,ter Kuile Feiko O.ORCID,Lacerda Marcus V. G.,Nasa Amit,Nosten François H.ORCID,Onyeji Cyprian O.,Pukrittayakamee Sasithon,Siqueira André M.ORCID,Tarning JoelORCID,Taylor Walter R. J.,Valentini Giovanni,van Vugt Michèle,Wesche David,Day Nicholas P. J.ORCID,Huang Christopher L-HORCID,Brugada Josep,Price Ric N.ORCID,White Nicholas J.ORCID

Publisher

Public Library of Science (PLoS)

Subject

General Medicine

Reference68 articles.

1. World Health Organization. World Malaria Report 2019. Geneva, Switzerland: 2019.

2. World Health Organization. Guidelines for the Treatment of Malaria. 3rd ed. Geneva, Switzerland. 2015.

3. ICH Harmonised Tripartite Guideline E14. The Clinical Evaluation of QT/QTc Interval Prolongation and Proarrhythmic Potential for Non-Antiarrhythmic Drugs. Internet. 2005 [cited 2019 Dec 3]. Available from: http://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Efficacy/E14/E14_Guideline.pdf.

4. Drug-induced prolongation of the QT interval;DM Roden;N Engl J Med,2004

5. World Health Organization. WHO Evidence Review Group on the Cardiotoxicity of Antimalarial Medicines. Geneva, Switzerland: 2017.

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