Abstract
Background
Escherichia coli O157:H7 (E. coli O157:H7) is one of the most potent zoonotic pathogens that causes mild diarrhea and leads to hemolytic uremic syndrome or death. This study was aimed to assess the prevalence and determinants of E. coli O157:H7 related to diarrhea among under-five children with acute diarrhea.
Methods
A cross-sectional study design was carried out in 2018 on 378 under-five-year children recruited randomly from hospitals in Eastern Ethiopia. Stool specimens were collected and processed using enrichment, differential and selective medium. Among isolates, E. coli O157:H7 was confirmed using latex test (Oxoid, Basingstoke, Hants, England). Factors associated with E. coli O157:H7 infection were identified using binary and multivariable logistic regression. Associations were reported by odds ratio with 95% confidence interval.
Results
The prevalence of E. coli O157:H7 related diarrhea was 15.3% (95%CI: 11.8–19.5). The E. coli O157:H7 infection was positively associated with rural residence (AOR;3.75, 95%CI:1.26–11.20), consumption of undercooked meat (AOR;3.95, 95%CI: 1.23–12.67), raw vegetables and/or fruit juice (AOR;3.37, 95%CI:1.32–8.62), presence of bloody diarrhea (AOR;4.42, 95% CI:1.78–10.94), number of under-five children in a household (AOR;7.16, 95%CI: 2.90–17.70), presence of person with diarrhea in a household (AOR;4.22, 95% CI: 1.84–12.69), owning domestic animal (AOR;3.87, 95% CI: 1.48–10.12) and uneducated mother (AOR;3.14, 95%CI: 1.05–9.42).
Conclusion
The Prevalence of E. coli O157:H7 related diarrhea among under-five children is relatively high in Eastern Ethiopia. The E. coli infection was associated with sanitation and hygiene in a household. Thus, education focused on food cooking and handling, child care, and household sanitation associated with animal manure in rural resident children are helpful in.
Publisher
Public Library of Science (PLoS)
Reference57 articles.
1. WHO UJSWHO. Progress on drinking water, sanitation and hygiene: 2017 update and SDG baselines. 2017.
2. Prevalence of diarrhea and associated factors among children under-five years of age in enderta woreda, tigray, northern ethiopia, 2014;H Berhe;International Journal of Therapeutic Applications,2016
3. Predictors of under-five childhood diarrhea: Mecha District, west Gojam, Ethiopia;M Dessalegn;Ethiopian journal of health development,2011
4. Prevalence and determinants of diarrhea among under-five children in Ethiopia: A systematic review and meta-analysis;A Alebel;PLoS One,2018
5. Outbreaks of Disease Associated with Food Imported into the United States, 1996-2014(1);LH Gould;Emerging infectious diseases,2017
Cited by
8 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献