Application of a Combination of a Knowledge-Based Algorithm and 2-Stage Screening to Hypothesis-Free Genomic Data on Irinotecan-Treated Patients for Identification of a Candidate Single Nucleotide Polymorphism Related to an Adverse Effect

Author:

Takahashi Hiro,Sai Kimie,Saito Yoshiro,Kaniwa Nahoko,Matsumura Yasuhiro,Hamaguchi Tetsuya,Shimada Yasuhiro,Ohtsu Atsushi,Yoshino Takayuki,Doi Toshihiko,Okuda Haruhiro,Ichinohe Risa,Takahashi Anna,Doi Ayano,Odaka Yoko,Okuyama Misuzu,Saijo Nagahiro,Sawada Jun-ichi,Sakamoto Hiromi,Yoshida Teruhiko

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

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5. Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28;H Minami;Pharmacogenet Genomics,2007

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