Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity

Author:

Guimarães Maria A.,de Oliveira Rosimeire N.,de Almeida Rebeca L.,Mafud Ana C.,Sarkis Ana L. V.,Ganassin Rayane,da Silva Marcos P.,Roquini Daniel B.,Veras Leiz M.,Sawada Tânia C. H.,Ropke Cristina D.,Muehlmann Luis A.,Joanitti Graziella A.,Kuckelhaus Selma A. S.,Allegretti Silmara M.,Mascarenhas Yvonne P.,de Moraes Josué,Leite José R. S. A.ORCID

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Foundation for Research Support of São Paulo State (FAPESP)

Phytobios Pesquisa Desenvolvimento e Inovação LTDA

Centroflora Group

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference44 articles.

1. Espécies de Pilocarpus vahl (RUTACEAE) da Amazônia Brasileira;LA Skorupa;Acta Amaz,2000

2. Anthelmintic, antibacterial and cytotoxicity activity of imidazole alkaloids from Pilocarpus microphyllus leaves;JA Rocha;Phytother Res,2017

3. Induction of pilocarpine formation in jaborandi leaves by salicylic acid and methyljasmonate;G Avancini;Phytochemistry,2003

4. Comparative vibrational spectra of pilosine and epiisopilosine crystals;RRF Bento;Braz J Phys,2010

5. Acute toxicological evaluation and hippocratic screening of epiisopilosine, secondary an alkaloid from Pilocarpus microphyllus Stapf;EMRA Lucio;Revi bras Farmacogn,2000

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