A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose-Reference-Cited by-同舟云学术

A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose

Published:2009-03-20 Issue:3 Volume:5 Page:e1000433
ISSN:1553-7404
Container-title:PLoS Genetics
language:en
Short-container-title:PLoS Genet

Author:

Takeuchi Fumihiko,McGinnis Ralph,Bourgeois Stephane,Barnes Chris,Eriksson Niclas,Soranzo Nicole,Whittaker Pamela,Ranganath Venkatesh,Kumanduri Vasudev,McLaren William,Holm Lennart,Lindh Jonatan,Rane Anders,Wadelius Mia,Deloukas Panos

Publisher

Public Library of Science (PLoS)

Subject

Cancer Research,Genetics (clinical),Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference44 articles.

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3. The largest prospective warfarin-treated cohort supports genetic forecasting.;M Wadelius;Blood,2009

4. Several-fold increase in risk of overanticoagulation by CYP2C9 mutations.;JD Lindh;Clin Pharmacol Ther,2005

5. Common VKORC1 and GGCX polymorphisms associated with warfarin dose.;M Wadelius;Pharmacogenomics J,2005

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