Common VKORC1 and GGCX polymorphisms associated with warfarin dose-Reference-Cited by-同舟云学术

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Common VKORC1 and GGCX polymorphisms associated with warfarin dose

Published:2005-05-10 Issue:4 Volume:5 Page:262-270
ISSN:1470-269X
Container-title:The Pharmacogenomics Journal
language:en
Short-container-title:Pharmacogenomics J

Author:

Wadelius M,Chen L Y,Downes K,Ghori J,Hunt S,Eriksson N,Wallerman O,Melhus H,Wadelius C,Bentley D,Deloukas P

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,Genetics,Molecular Medicine

Link

http://www.nature.com/articles/6500313.pdf

Reference47 articles.

1. Scordo MG, Pengo V, Spina E, Dahl ML, Gusella M, Padrini R . Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance. Clin Pharmacol Ther 2002; 72: 702–710.

2. Aithal G, Day C, Kesteven P, Daly A . Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications. Lancet 1999; 353: 689–717.

3. Wadelius M, Sörlin K, Wallerman O, Karlsson J, Yue QY, Magnusson PK et al. Warfarin sensitivity related to CYP2C9, CYP3A5, ABCB1 (MDR1) and other factors. Pharmacogenomics J 2004; 4: 40–48.

4. van den Besselaar AM . Standardization of the prothrombin time in oral anticoagulant control. Haemostasis 1985; 15: 271–277.

5. Takahashi H, Echizen H . Pharmacogenetics of CYP2C9 and interindividual variability in anticoagulant response to warfarin. Pharmacogenomics J 2003; 3: 202–214.

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