Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals

Author:

Chan Yingleong,Holmen Oddgeir L.,Dauber Andrew,Vatten Lars,Havulinna Aki S.,Skorpen Frank,Kvaløy Kirsti,Silander Kaisa,Nguyen Thutrang T.,Willer Cristen,Boehnke Michael,Perola Markus,Palotie Aarno,Salomaa Veikko,Hveem Kristian,Frayling Timothy M.,Hirschhorn Joel N.,Weedon Michael N.

Publisher

Public Library of Science (PLoS)

Subject

Cancer Research,Genetics (clinical),Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference22 articles.

1. Genome partitioning of genetic variation for height from 11,214 sibling pairs.;PM Visscher;Am J Hum Genet,2007

2. Hundreds of variants clustered in genomic loci and biological pathways affect human height.;H Lango Allen;Nature,2010

3. Missing heritability and strategies for finding the underlying causes of complex disease.;EE Eichler;Nat Rev Genet,2010

4. Uncovering the roles of rare variants in common disease through whole-genome sequencing.;ET Cirulli;Nat Rev Genet,2010

5. Finding the missing heritability of complex diseases.;TA Manolio;Nature,2009

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