Is Non-Homologous End-Joining Really an Inherently Error-Prone Process?

Author:

Bétermier Mireille,Bertrand Pascale,Lopez Bernard S.

Publisher

Public Library of Science (PLoS)

Subject

Cancer Research,Genetics(clinical),Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference97 articles.

1. Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends;J Guirouilh-Barbat;Proc Natl Acad Sci U S A,2007

2. Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells;J Guirouilh-Barbat;Mol Cell,2004

3. Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joining;A Grabarz;Am J Cancer Res,2012

4. Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining;M Audebert;J Biol Chem,2004

5. Rag mutations reveal robust alternative end joining;B Corneo;Nature,2007

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