Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits
Author:
Publisher
Public Library of Science (PLoS)
Subject
Cancer Research,Genetics (clinical),Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics
Reference89 articles.
1. Lessons from 60 years of pharmaceutical innovation;B Munos;Nat Rev Drug Discov,2009
2. Trial watch: Phase II failures: 2008–2010;J Arrowsmith;Nat Rev Drug Discov,2011
3. Translational genomics. Targeting the host immune response to fight infection;JK Baillie;Science,2014
4. The support of human genetic evidence for approved drug indications;MR Nelson;Nat Genet,2015
5. The druggable genome and support for target identification and validation in drug development;C Finan;Sci Transl Med,2017
Cited by 30 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. The genetic landscape of neuro-related proteins in human plasma;Nature Human Behaviour;2024-08-29
2. Investigating potential novel therapeutic targets and biomarkers for ankylosing spondylitis using plasma protein screening;Frontiers in Immunology;2024-08-09
3. Instrumental variable and colocalization analyses identify endotrophin and HTRA1 as potential therapeutic targets for coronary artery disease;iScience;2024-07
4. Genetic determinants of plasma protein levels in the Estonian population;Scientific Reports;2024-04-02
5. Inflammation proteomics datasets in the ALSPAC cohort;Wellcome Open Research;2024-02-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3