Resection and repair of a Cas9 double-strand break at CTG trinucleotide repeats induces local and extensive chromosomal deletions
Author:
Publisher
Public Library of Science (PLoS)
Subject
Cancer Research,Genetics(clinical),Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics
Reference63 articles.
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2. CRISPR/Cas9-mediated deletion of a GA-repeat in human GPM6B leads to disruption of neural cell differentiation from NT2 cells;Scientific Reports;2024-01-25
3. CRISPR/Cas9-induced double-strand breaks in huntingtin locus lead to CAG repeat contraction through the extensive DNA end resection and homology-mediated repair;2023-11-24
4. TALEN-induced contraction of CTG trinucleotide repeats in myotonic dystrophy type 1 cells;2023-10-18
5. Structure-forming CAG/CTG repeats interfere with gap repair to cause repeat expansions and chromosome breaks;Nature Communications;2023-04-29
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