Daily zeaxanthin supplementation prevents atrophy of the retinal pigment epithelium (RPE) in a mouse model of mitochondrial oxidative stress

Author:

Biswal Manas R.ORCID,Justis Bradley D.,Han Pingyang,Li Hong,Gierhart Dennis,Dorey Cheryl K.,Lewin Alfred S.

Funder

ZeaVision LLC, National Eye Institute, Bright Focus Foundation

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference51 articles.

1. Age-Related Macular Degeneration: Facts & Figures (2016). Bright Focus Foundation. http://www.brightfocus.org/macular/article/age-related-macular-facts-figures:; date last accessed Oct 22, 2017. Epub; date last accessed Oct 22, 2017.

2. Evolution of geographic atrophy of the retinal pigment epithelium;JP Sarks;Eye (Lond),1988

3. The retinal pigment epithelium in visual function;O. Strauss;Physiol Rev,2005

4. The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD;S Datta;Prog Retin Eye Res,2017

5. Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium;F Schutt;Invest Ophthalmol Vis Sci,2003

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