Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers II: Sigma-2/PGRMC1 Receptors Mediate Abeta 42 Oligomer Binding and Synaptotoxicity

Author:

Izzo Nicholas J.,Xu Jinbin,Zeng Chenbo,Kirk Molly J.,Mozzoni Kelsie,Silky Colleen,Rehak Courtney,Yurko Raymond,Look Gary,Rishton Gilbert,Safferstein Hank,Cruchaga Carlos,Goate Alison,Cahill Michael A.,Arancio Ottavio,Mach Robert H.,Craven Rolf,Head Elizabeth,LeVine Harry,Spires-Jones Tara L.,Catalano Susan M.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference60 articles.

1. Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum;WL Klein;Trends Neurosci,2001

2. Neurotoxicity of Amyloid beta-Protein: Synaptic and Network Dysfunction;L Mucke;Cold Spring Harb Perspect Med,2012

3. Different beta-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity;F Bao;Neurobiol Aging,2012

4. Detection of a biomarker for Alzheimer's disease from synthetic and clinical samples using a nanoscale optical biosensor;AJ Haes;J Am Chem Soc,2005

5. Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction;JL Tomic;Neurobiol Dis,2009

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