An interim exploratory proteomics biomarker analysis of a phase 2 clinical trial to assess the impact of CT1812 in Alzheimer's disease-Reference-Cited by-同舟云学术

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An interim exploratory proteomics biomarker analysis of a phase 2 clinical trial to assess the impact of CT1812 in Alzheimer's disease

Published:2024-09 Issue: Volume:199 Page:106575
ISSN:0969-9961
Container-title:Neurobiology of Disease
language:en
Short-container-title:Neurobiology of Disease

Author:

Lizama B.N.,North H.A.,Pandey K.,Williams C.,Duong D.,Cho E.,Di Caro V.,Ping L.,Blennow K.,Zetterberg H.,Lah J.,Levey A.I.,Grundman M.,Caggiano A.O.,Seyfried N.T.,Hamby M.E.

Funder

ADDF

NIA

Publisher

Elsevier BV

Reference61 articles.

1. Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring;Ashton;Nat. Med.,2022

2. Biomarker potential of brain-secreted extracellular vesicles in blood in Alzheimer’s disease;Badhwar;Alzheimer’s Dement.,2020

3. Clusterin binds to Aβ1-42 oligomers with high affinity and interferes with peptide aggregation by inhibiting primary and secondary nucleation;Beeg;J. Biol. Chem.,2016

4. Multi-cohort profiling reveals elevated CSF levels of brain-enriched proteins in Alzheimer’s disease;Bergström;Ann. Clin. Transl. Neurol.,2021

5. Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease;Bertrand;Brain Res. Mol. Brain Res.,1995

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. CT1812 biomarker signature from a meta‐analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer's disease;Alzheimer's & Dementia;2024-08-21

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