Using unsupervised machine learning to quantify physical activity from accelerometry in a diverse and rapidly changing population

Abstract

Accelerometers are widely used to measure physical activity behaviour, including in children. The traditional method for processing acceleration data uses cut points to define physical activity intensity, relying on calibration studies that relate the magnitude of acceleration to energy expenditure. However, these relationships do not generalise across diverse populations and hence they must be parametrised for each subpopulation (e.g., age groups) which is costly and makes studies across diverse populations and over time difficult. A data-driven approach that allows physical activity intensity states to emerge from the data, without relying on parameters derived from external populations, offers a new perspective on this problem and potentially improved results. We applied an unsupervised machine learning approach, namely a hidden semi-Markov model, to segment and cluster the raw accelerometer data recorded (using a waist-worn ActiGraph GT3X+) from 279 children (9–38 months old) with a diverse range of developmental abilities (measured using the Paediatric Evaluation of Disability Inventory–Computer Adaptive Testing measure). We benchmarked this analysis with the cut points approach, calculated using thresholds from the literature which had been validated using the same device and for a population which most closely matched ours. Time spent active as measured by this unsupervised approach correlated more strongly with PEDI-CAT measures of the child’s mobility (R2: 0.51 vs 0.39), social-cognitive capacity (R2: 0.32 vs 0.20), responsibility (R2: 0.21 vs 0.13), daily activity (R2: 0.35 vs 0.24), and age (R2: 0.15 vs 0.1) than that measured using the cut points approach. Unsupervised machine learning offers the potential to provide a more sensitive, appropriate, and cost-effective approach to quantifying physical activity behaviour in diverse populations, compared to the current cut points approach. This, in turn, supports research that is more inclusive of diverse or rapidly changing populations.