Hot-spot identification on a broad class of proteins and RNA suggest unifying principles of molecular recognition
Author:
Funder
National Institute of General Medical Sciences
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference121 articles.
1. Fragment growing induces conformational changes in acetylcholine-binding protein: a structural and thermodynamic analysis;E Edink;J Am Chem Soc,2011
2. Nanomolar E-selectin antagonists with prolonged half-lives by a fragment-based approach;J Egger;J Am Chem Soc,2013
3. Small-molecule binding sites on proteins established by paramagnetic NMR spectroscopy;JY Guan;J Am Chem Soc,2013
4. Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains;DA Hay;J Am Chem Soc,2014
5. Electrophilic fragment-based design of reversible covalent kinase inhibitors;RM Miller;J Am Chem Soc,2013
Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. BMaps: A Web Application for Fragment-Based Drug Design and Compound Binding Evaluation;Journal of Chemical Information and Modeling;2023-07-05
2. Computational Tools and Strategies to Develop Peptide-Based Inhibitors of Protein-Protein Interactions;Methods in Molecular Biology;2021-07-08
3. Identification and characterization of fragment binding sites for allosteric ligand design using the site identification by ligand competitive saturation hotspots approach (SILCS-Hotspots);Biochimica et Biophysica Acta (BBA) - General Subjects;2020-04
4. Fragment-based design of small molecule PCSK9 inhibitors using simulated annealing of chemical potential simulations;PLOS ONE;2019-12-05
5. Spectral analysis of molecular dynamics simulations on PDZ: MD sectors;Journal of Biomolecular Structure and Dynamics;2019-07-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3