A Chimeric HS4-SAR Insulator (IS2) That Prevents Silencing and Enhances Expression of Lentiviral Vectors in Pluripotent Stem Cells
Author:
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference45 articles.
1. The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy;E Montini;J Clin Invest,2009
2. Biochemical correction of X-CGD by a novel chimeric promoter regulating high levels of transgene expression in myeloid cells;G Santilli;Mol Ther,2011
3. Stable gene expression occurs from a minority of integrated HIV-1-based vectors: transcriptional silencing is present in the majority;HP Mok;Gene Ther,2007
4. Silencing and variegation of gammaretrovirus and lentivirus vectors;J Ellis;Hum Gene Ther,2005
5. Transcriptional provirus silencing as a crosstalk of de novo DNA methylation and epigenomic features at the integration site;F Senigl;Nucleic Acids Res,2012
Cited by 31 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. First-in-classTransactivator-Free, Doxycycline-inducible IL-18-engineered CAR-T cells for relapsed/refractory B-cell lymphomas;2024-01-25
2. Lentiviral gene therapy reverts GPIX expression and phenotype in Bernard-Soulier syndrome type C;Molecular Therapy - Nucleic Acids;2023-09
3. Development of an Expression Vector Engineering Strategy Based on tDNA Insulator Element for the Stable Expression of Vascular Endothelial Growth Factor Receptor-Fc Fusion Protein;Monoclonal Antibodies in Immunodiagnosis and Immunotherapy;2023-08-01
4. Lentiviral vectors for inducible, transactivator-free advanced therapy medicinal products: Application to CAR-T cells;Molecular Therapy - Nucleic Acids;2023-06
5. Physiological lentiviral vectors for the generation of improved CAR-T cells;Molecular Therapy - Oncolytics;2022-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3