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IL-13 Promotes Collagen Accumulation in Crohn’s Disease Fibrosis by Down-Regulation of Fibroblast MMP Synthesis: A Role for Innate Lymphoid Cells?

  • Published:2012-12-31 Issue:12 Volume:7 Page:e52332
  • ISSN:1932-6203
  • Container-title:PLoS ONE
  • language:en
  • Short-container-title:PLoS ONE

Author:

Bailey Jennifer R.,Bland Paul W.,Tarlton John F.,Peters Iain,Moorghen Moganaden,Sylvester Paul A.,Probert Christopher S. J.,Whiting Christine V.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference40 articles.

1. Fibrogenesis in Crohn’s disease;JP Burke;Am J Gastroenterol,2007

2. Stimulation of transforming growth factor beta1 by enteric bacteria in the pathogenesis of rat intestinal fibrosis;M Mourelle;Gastroenterology,1998

3. IL-13 effector functions;TA Wynn;Annu Rev Immunol,2003

4. Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblasts;A Oriente;J Pharmacol Exp Ther,2000

5. Obliterative muscularization of the small bowel submucosa in Crohn disease: a possible mechanism of small bowel obstruction;G Koukoulis;Arch Pathol Lab Med,2001

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