Reorienting the Fab Domains of Trastuzumab Results in Potent HER2 Activators-Reference-Cited by-同舟云学术

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Reorienting the Fab Domains of Trastuzumab Results in Potent HER2 Activators

Published:2012-12-20 Issue:12 Volume:7 Page:e51817
ISSN:1932-6203
Container-title:PLoS ONE
language:en
Short-container-title:PLoS ONE

Author:

Scheer Justin M.,Sandoval Wendy,Elliott J. Michael,Shao Lily,Luis Elizabeth,Lewin-Koh Sock-Cheng,Schaefer Gabriele,Vandlen Richard

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference33 articles.

1. Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index;JR Junutula;Nature Biotechnology,2008

2. Engineered thio-trastuzumab-DM1 conjugate with an improved therapeutic index to target human epidermal growth factor receptor 2-positive breast cancer;JR Junutula;Clinical Cancer Research,2010

3. Therapeutic potential of an anti-CD79b antibody-drug conjugate, anti-CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma;D Dornan;Blood,2009

4. Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs;JR Junutula;J Immunol Methods,2008

5. The epidermal growth factor receptor family: biology driving targeted therapeutics;MJ Wieduwilt;Cell Mol Life Sci,2008

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