MYC Cooperates with AKT in Prostate Tumorigenesis and Alters Sensitivity to mTOR Inhibitors

Author:

Clegg Nicola J.,Couto Suzana S.,Wongvipat John,Hieronymus Haley,Carver Brett S.,Taylor Barry S.,Ellwood-Yen Katharine,Gerald William L.,Sander Chris,Sawyers Charles L.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference47 articles.

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2. Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis.;HI Scher;J Clin Oncol,2005

3. Recurrent gene fusions in prostate cancer.;C Kumar-Sinha;Nat Rev Cancer,2008

4. Akt-regulated pathways in prostate cancer.;PK Majumder;Oncogene,2005

5. Detection of c-myc oncogene amplification and chromosomal anomalies in metastatic prostatic carcinoma by fluorescence in situ hybridization.;RB Jenkins;Cancer Res,1997

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