CpG stimulation of chronic lymphocytic leukemia cells induces a polarized cell shape and promotes migration in vitro and in vivo

Author:

Dampmann MariaORCID,Görgens AndréORCID,Möllmann Michael,Murke Florian,Dührsen Ulrich,Giebel Bernd,Dürig Jan

Funder

Wiedenfeldstiftung

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference26 articles.

1. Bcl-2 expression in chronic lymphocytic leukemia and its correlation with the induction of apoptosis and clinical outcome;LE Robertson;Leukemia,1996

2. Antisense-mediated suppression of Bcl-2 highlights its pivotal role in failed apoptosis in B-cell chronic lymphocytic leukaemia;C Pepper;Br J Haematol,1999

3. Phase I to II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in patients with advanced chronic lymphocytic leukemia;SM O’Brien;J Clin Oncol,2005

4. Randomized phase III trial of fludarabine plus cyclophosphamide with or without oblimersen sodium (Bcl-2 antisense) in patients with relapsed or refractory chronic lymphocytic leukemia;S O’Brien;J Clin Oncol,2007

5. CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens;B Jahrsdörfer;J Leukoc Biol,2001

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