Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool
Author:
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference20 articles.
1. Deep mutational scanning: a new style of protein science;DM Fowler;Nature Methods,2014
2. The new frontier of genome engineering with CRISPR-Cas9;JA Doudna;Science,2014
3. Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9;JG Doench;Nat Biotechnol,2016
4. Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells;O Shalem;Science,2014
5. DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks;M van Overbeek;Mol Cell,2016
Cited by 50 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. DNA polymerase λ-driven targeted mutagenesis for directed evolution in human cells;2024-07-24
2. Uncovering the bookshelves of CRISPR-based libraries: Advances and applications in cancer studies;Critical Reviews in Oncology/Hematology;2024-04
3. Applications of CRISPR-Cas9 for advancing precision medicine in oncology: from target discovery to disease modeling;Frontiers in Genetics;2023-10-16
4. Target identification of small molecules: an overview of the current applications in drug discovery;BMC Biotechnology;2023-10-10
5. CRISPR tiling screen reveals cancer epigenetic ‘Goldilocks’ state;Trends in Pharmacological Sciences;2023-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3