Ex vivo activation of CD4+ T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells-Reference-Cited by-同舟云学术

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Ex vivo activation of CD4+ T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells

Published:2017-02-22 Issue:2 Volume:13 Page:e1006230
ISSN:1553-7374
Container-title:PLOS Pathogens
language:en
Short-container-title:PLoS Pathog

Author:

Bui John K.^ORCID,Halvas Elias K.^ORCID,Fyne Elizabeth,Sobolewski Michele D.,Koontz Dianna^ORCID,Shao Wei,Luke Brian,Hong Feiyu F.,Kearney Mary F.,Mellors John W.

Funder

Howard Hughes Medical Institute

Leidos Biomedical Research

National Cancer Institute

Bill and Melinda Gates Foundation

Publisher

Public Library of Science (PLoS)

Subject

Virology,Genetics,Molecular Biology,Immunology,Microbiology,Parasitology

Reference42 articles.

1. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy;D Finzi;Science,1997

2. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia;JK Wong;Science,1997

3. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy;D Finzi;Nature Medicine,1999

4. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection;TW Chun;Nature,1997

5. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells;JD Siliciano;Nature Medicine,2003

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