Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease-Reference-Cited by-同舟云学术

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Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

Published:2010-04-01 Issue:4 Volume:5 Page:e9979
ISSN:1932-6203
Container-title:PLoS ONE
language:en
Short-container-title:PLoS ONE

Author:

Spilman Patricia,Podlutskaya Natalia,Hart Matthew J.,Debnath Jayanta,Gorostiza Olivia,Bredesen Dale,Richardson Arlan,Strong Randy,Galvan Veronica

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference50 articles.

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2. Extension of chronological life span in yeast by decreased TOR pathway signaling.;RW Powers 3rd;Genes Dev,2006

3. The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span.;K Jia;Development,2004

4. Genetics: influence of TOR kinase on lifespan in C. elegans.;T Vellai;Nature,2003

5. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.;DE Harrison;Nature,2009

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