Downregulation of Histone H3 Lysine 9 Methyltransferase G9a Induces Centrosome Disruption and Chromosome Instability in Cancer Cells
Author:
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference27 articles.
1. Translating the histone code.;T Jenuwein;Science,2001
2. Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability.;AH Peters;Cell,2001
3. Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3.;M Tachibana;J Biol Chem,2001
4. SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins.;DC Schultz;Genes Dev,2002
5. A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells.;H Ogawa;Science,2002
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