A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis

Author:

MacGregor PaulaORCID,Gonzalez-Munoz Andrea L.,Jobe Fatoumatta,Taylor Martin C.,Rust Steven,Sandercock Alan M.,Macleod Olivia J. S.ORCID,Van Bocxlaer Katrien,Francisco Amanda F.,D’Hooge Francois,Tiberghien ArnaudORCID,Barry Conor S.,Howard Philip,Higgins Matthew K.,Vaughan Tristan J.,Minter Ralph,Carrington MarkORCID

Funder

Medical Research Council

Biotechnology and Biological Sciences Research Council

Publisher

Public Library of Science (PLoS)

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

Reference76 articles.

1. Human African trypanosomiasis in Working to overcome the global impact of neglected tropical diseases;First WHO report on neglected tropical diseases,2010

2. Clinical features, diagnosis, and treatment of human African trypanosomiasis (sleeping sickness);PG Kennedy;Lancet Neurol,2013

3. Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need;MC Field;Nat Rev Microbiol,2017

4. A current analysis of chemotherapy strategies for the treatment of human African trypanosomiasis;P Babokhov;Pathog Glob Health,2013

5. A haptoglobin-hemoglobin receptor conveys innate immunity to Trypanosoma brucei in humans;B Vanhollebeke;Science,2008

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