Antimicrobial Activity of Some Essential Oils Against Pseudomonas aeruginosa

Abstract

AbstractThe emergence of multidrug resistance in bacteria due to overuse of antibiotics is becoming an important health concern in recent years, which requires development of novel alternatives to fight against these bacteria. Essential oils (EOs) are secondary metabolites that have different components and chemical compositions which may provide promising solution to the problem of rising number of drug resistant bacteria, as they can effectively kill bacteria. Here, in this study our aim is to determine the efficacy of lemongrass, rosemary, clary sage, geranium and tea tree essential oil against Pseudomonas aeruginosa, using agar well diffusion method. The minimum inhibitory concentration (MIC) of these EOs were also determined. The chemical composition of these essential oils were known by gas chromatography-mass spectrometry (GC-MS) analysis. It was revealed in this study that most of the essential oils show antimicrobial property against the test bacterium. The MIC of lemongrass is 0.25% (v/v), rosemary is 1% (v/v), clary sage is 2% (v/v), geranium is 0.5% (v/v) and for tea tree oil is 1% (v/v). We can infer from this data that lemongrass, rosemary, clary sage, geranium and tree oil can be utilized to treat infections caused by Pseudomonas aeruginosa, which is a gram-negative bacterium.