Effect of chitosan application on lung tissue in rats with experimental fluorine toxicity-Reference-Cited by-同舟云学术

Effect of chitosan application on lung tissue in rats with experimental fluorine toxicity

Published:2022-07-20 Issue:4 Volume:5 Page:969-972
ISSN:2636-8579
Container-title:Journal of Health Sciences and Medicine
language:en
Short-container-title:J Health Sci Med / JHSM

Author:

BULDUK Bahattin¹

Affiliation:

1. VAN YÜZÜNCÜ YIL ÜNİVERSİTESİ SAĞLIK BİLİMLERİ FAKÜLTESİ

Abstract

Aim: The aim of this study is to investigate the effects of chitosan application on lung tissue in rats with experimental fluorine toxicity. Material and Method: In the study, 21 healthy male wistar albino rats were used. Prior to the trial, the acclimation of the rats was provided. 3 groups were randomly generated in a way that there were 7 rats in each group. These were determined as the control group (C), the fluorosis group (NaF) and the fluorosis + chitosan (NaF+CS) group. Results: In the NaF group, CAT, SOD and GSH values were found to be low compared to other groups and MDA values were found to be high. It was found that the chitosan application reduced the CAT, SOD and GSH values, and increased the MDA value. Conclusion: It has been predicted that chitosan application may be beneficial in preventing cellular damage that may occur with fluorine exposure.

Publisher

Journal of Health Sciences and Medicine

Subject

General Medicine

Reference31 articles.

1. Altındağ F, Özdek U. Protective effects of chitosan and chitosan oligosaccharide on sodium fluoride-induced testicular damage in male rats: a stereological and histopathological study. Kafkas Üniversitesi Veteriner Fakültesi Derg 2021; 27: 183-9.

2. Comba B. Hayvanlarda florozis, teşhis, tedavi ve koruma. Yüzüncü Yıl Üniversitesi Veteriner Fakültesi Derg 2013; 24: 41-

3. Bulduk B, Uyar H, Oto G, et al. Effect Of exposure to fluorine and 7, 12-dimethyl benzanthracene on vascular responses. Fresenius Environmental Bulletin 2022; 31: 2826-31.

4. Varol E, Varol S. Çevresel bir hastalık olarak florozis ve insan sağlığı üzerine etkisi. SDÜ Fen Bilimleri Enstitüsü, TAF Preventive Medicine Bulletin 2010; 9: 233-8.

5. Wei W, Pang S, Sun D. The pathogenesis of endemic fluorosis: Research progress in the last 5 years. IJMCM 2019; 23: 2333-42.

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