Two cases of verified clinical failures using internationally recommended first-line cefixime for gonorrhoea treatment, Norway, 2010-Reference-Cited by-同舟云学术

Two cases of verified clinical failures using internationally recommended first-line cefixime for gonorrhoea treatment, Norway, 2010

Published:2010-11-25 Issue:47 Volume:15 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Unemo M¹,Golparian D¹,Syversen G²,Vestrheim D F³⁴,Moi H⁵⁴

Affiliation:

1. Swedish Reference Laboratory for Pathogenic Neisseria, Department of Laboratory Medicine, Microbiology, Örebro University Hospital, Örebro, Sweden

2. Department of Microbiology, Oslo University Hospital, Ullevål, Oslo, Norway

3. Division of Infectious Disease Control, Norwegian Institute of Public Health, Oslo, Norway

4. Olafiaklinikken, Oslo University Hospital, Oslo, Norway

5. Faculty of Medicine, University of Oslo, Oslo, Norway

Abstract

Neisseria gonorrhoeae has developed resistance to most of the available therapeutic antimicrobials. The susceptibility to extended-spectrum cephalosporins, the last remaining first-line treatment option, is decreasing globally. This report describes the first two cases outside Japan of verified gonorrhoea clinical failures using internationally recommended first-line cefixime treatment. Enhanced awareness and more frequent follow-up examination, test-of-cure and appropriate verification/falsification of presumed clinical treatment failures, involving several clinical and laboratory parameters should be strongly emphasised worldwide.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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