Isolation of infectious Zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the Dominican Republic to Italy, January 2016-Reference-Cited by-同舟云学术

Isolation of infectious Zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the Dominican Republic to Italy, January 2016

Published:2016-03-10 Issue:10 Volume:21 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Barzon Luisa¹²,Pacenti Monia²,Berto Alessandro¹,Sinigaglia Alessandro³,Franchin Elisa¹²,Lavezzo Enrico¹,Brugnaro Pierluigi⁴,Palù Giorgio¹²

Affiliation:

1. Department of Molecular Medicine, University of Padova, Padova, Italy

2. Microbiology and Virology Unit, Padova University Hospital, Padova, Italy

3. Veneto Institute of Oncology IOV IRCCS, Padova, Italy

4. Infectious Disease Department, Venice City Hospital ‘SS. Giovanni e Paolo’, Venice, Italy

Abstract

We report the isolation of infectious Zika virus (ZIKV) in cell culture from the saliva of a patient who developed a febrile illness after returning from the Dominican Republic to Italy, in January 2016. The patient had prolonged shedding of viral RNA in saliva and urine, at higher load than in blood, for up to 29 days after symptom onset. Sequencing of ZIKV genome showed relatedness with strains from Latin America.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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